Investigation of the Matabolite Profile of Acoziborole in Plasma Urine and Fecal Homogenate Samples Using UPLC-MS Fractionation Followed by AMS Analysis

Acoziborole, an oxaborole-6 carboxamide, is being developed as an oral single dose treatment for Human African Trypanosomiasis. This poster will describe the metabolite characterization investigations following the human ADME studying a microdose of [14C]-Acoziborole.